All these routines create system-specific portability problems. As noted elsewhere, Perl is at the mercy of your C libraries for much of its system behaviour. It's probably safest to assume broken SysV semantics for signals and to stick with simple TCP and UDP socket operations; e.g., don't try to pass open file descriptors over a local UDP datagram socket if you want your code to stand a chance of being portable.

Because few vendors provide C libraries that are safely re-entrant, the prudent programmer will do little else within a handler beyond die to raise an exception and longjmp out.